Sickle Cell Anemia Research Today is a free monthly online journal that collates and summarizes the latest research about Sickle Cell Anemia, including details on genetics, causes, symptoms.

Sickle cell disease: old discoveries, new concepts, and future promise.

Frenette PS, Atweh GF

Division of Hematology/Oncology, Mount Sinai School of Medicine, New York, New York 10029, USA.

The discovery of the molecular basis of sickle cell disease was an important landmark in molecular medicine. The modern tools of molecular and cellular biology have refined our understanding of its pathophysiology and facilitated the development of new therapies. In this review, we discuss some of the important advances in this field and the impediments that limit the impact of these advances.

Published 3 April 2007 in J Clin Invest, 117(4): 850-8.
Full-text of this article is available online (may require subscription).

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